Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505568 | 0.92 | ACAT1 (0.60) | ACAT1SMPD1MAPTMEN1KMT2A | |
| SCHEMBL9503848 | 0.92 | ACAT1 (0.60) | ACAT1SMPD1MAPTMEN1KMT2A | |
| SCHEMBL9361436 | 0.91 | ACAT1 (0.67) | ACAT1SMPD1MAPTTP53GAA | |
| SCHEMBL9361238 | 0.91 | ACAT1 (0.67) | ACAT1SMPD1MAPTTP53GAA | |
| SCHEMBL9502181 | 0.91 | SMPD1 (0.55) | ACAT1SMPD1MAPTMEN1KMT2A | |
| SCHEMBL9361158 | 0.90 | ACAT1 (0.65) | ACAT1SMPD1MAPTMEN1KMT2A | |
| SCHEMBL9502105 | 0.89 | ACAT1 (0.57) | ACAT1MAPTMEN1KMT2AHTT | |
| SCHEMBL9505446 | 0.89 | ACAT1 (0.57) | ACAT1MAPTMEN1KMT2AHTT | |
| SCHEMBL9502255 | 0.88 | ACAT1 (0.72) | ACAT1MAPTMEN1KMT2AHTT | |
| SCHEMBL9502212 | 0.88 | ACAT1 (0.72) | ACAT1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543891-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |