Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503848 | 1.00 | ACAT1 (0.60) | ACAT1SMPD1MEN1KMT2AHTT | |
| SCHEMBL9502181 | 0.95 | SMPD1 (0.55) | ACAT1SMPD1MEN1KMT2AHTT | |
| SCHEMBL9506207 | 0.92 | ACAT1 (0.55) | ACAT1SMPD1MEN1KMT2AHTT | |
| SCHEMBL9362298 | 0.90 | ACAT1 (0.73) | ACAT1SMPD1MAPTTP53GAA | |
| SCHEMBL9362439 | 0.90 | ACAT1 (0.73) | ACAT1SMPD1MAPTTP53GAA | |
| SCHEMBL9365181 | 0.90 | ACAT1 (0.73) | ACAT1SMPD1MAPTTP53GAA | |
| SCHEMBL9503105 | 0.89 | PLA2G4B (0.60) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL9361174 | 0.89 | ACAT1 (0.71) | ACAT1SMPD1MEN1KMT2AMAPT | |
| SCHEMBL9502491 | 0.88 | ACAT1 (0.62) | ACAT1MEN1KMT2AHTTMAPT | |
| SCHEMBL9502984 | 0.88 | ACAT1 (0.62) | ACAT1MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543891-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |