Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042796 | 0.95 | CA1 (0.55) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL28154687 | 0.93 | CA2 (0.67) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL15942757 | 0.92 | CA1 (0.49) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL11615218 | 0.90 | TSHR (0.56) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL487286 | 0.89 | CA2 (0.58) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL28273234 | 0.89 | CA2 (0.58) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL8107918 | 0.89 | TSHR (0.54) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL579709 | 0.89 | CA1 (0.50) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL27966661 | 0.87 | CA2 (0.65) | CA1CA2TSHRZDHHC7L3MBTL1 | |
| SCHEMBL7858108 | 0.87 | CA2 (0.69) | CA1CA2TSHRZDHHC7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471021-B | Substituted diamino carboxamides and diamino carbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115947681-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-109641844-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-113727973-A | Substituted amide compounds useful as farnesoid X receptor modulators | 百时美施贵宝公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113226296-A | SSAO inhibitors and uses thereof | 梅塔科林公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-112204009-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-112189008-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-106061971-B | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2019-03-12 | — | — | CN | disclosed |
| US-9809668-B2 | Polymerizable compound, composition, polymer, optically anisotropic body, liquid crystal display device, and organic EL device | DIC CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20170260150-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY ELEMENT, AND ORGANIC EL DEVICE | DIC CORPORATION (JP) | 2017-09-14 | — | — | US | disclosed |
| US-20170029655-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | DIC CORPORATION (JP) | 2017-02-02 | — | — | US | disclosed |
| US-20170002123-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | DIC CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
| CN-106061971-A | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104592231-A | Novel Tricyclic Compounds | ABBVIE INC | 2015-05-06 | — | — | CN | disclosed |
| EP-0338427-B1 | PROCESS FOR THE PREPARATION OF ESTERS OLEFINIC UNSATURATED CARBOXYLIC ACIDS WITH A TERMINAL ESTER GROUP | BASF Aktiengesellschaft (DE) | 1993-08-18 | — | — | EP | disclosed |
| EP-0338427-A2 | Process for the preparation of esters olefinic unsaturated carboxylic acids with a terminal ester group | BASF Aktiengesellschaft (DE) | 1989-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260150-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY ELEMENT, AND ORGANIC EL DEVICE | RPL19, RPL24, RPL29 | CA1 1476/4885CA2 3995/4885TSHR 4519/4885 |
| US-20170002123-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | OCIAD1, OCIAD2, ELOC | CA1 1813/4885CA2 4079/4885TSHR 4711/4885 |
| US-20170029655-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | OCIAD1, OCIAD2, ELOC | CA1 1813/4885CA2 4079/4885TSHR 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.