Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503238 | 0.85 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL10701160 | 0.85 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL9507014 | 0.85 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL12267639 | 0.84 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL9507059 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL9506253 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL13663629 | 0.81 | CTSL (0.52) | NR1H2NR1H3SRC | |
| SCHEMBL30923999 | 0.80 | NR1H2 (0.41) | NR1H2SRC | |
| SCHEMBL1224618 | 0.80 | SRC (0.46) | NR1H2NR1H3SRC | |
| SCHEMBL14981703 | 0.78 | SRC (0.44) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |