SCHEMBL9506278

SCHEMBL9506278

CC(Oc1ccccc1Oc1ccccc1F)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.63
ALDH1A1 P00352 2/20 0.55
GAA P10253 2/20 0.55
LMNA P02545 3/20 0.51
HPGD P15428 1/20 0.50
CXCL8 P10145 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
PKM P14618 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CARM1 Q86X55 2/20 0.44
PRMT6 Q96LA8 2/20 0.44
SLC1A5 Q15758 1/20 0.44
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29249699 0.90 GAA (0.66) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL9780972 0.90 GAA (0.66) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL9780966 0.90 GAA (0.66) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL10563315 0.89 KMT2A (0.58) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL12667937 0.84 GAA (0.59) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL28483915 0.83 KMT2A (0.67) KMT2AGAALMNAPPARGPPARA
SCHEMBL9173964 0.83 KMT2A (0.54) KMT2AALDH1A1GAALMNAHPGD
SCHEMBL1538036 0.81 KMT2A (0.69) KMT2AGAALMNAPPARGPPARA
SCHEMBL10480779 0.81 PTGDR2 (0.50) KMT2AALDH1A1GAASMN1; SMN2CARM1
SCHEMBL9633119 0.80 ALDH1A1 (0.48) KMT2AALDH1A1GAALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389056-B1 PREPARATION OF FLUOROPHENOLS DowElanco (US) 1993-08-04 EP disclosed
EP-0389056-A1 Preparation of fluorophenols DowElanco (US) 1990-09-26 EP disclosed
US-4940821-A CHLOROFLUOROBENZENE, WATER, COPPER SALT THE DOW CHEMICAL COMPANY (US) 1990-07-10 US disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
EP-0138359-B1 HERBICIDAL FLUOROPHENOXYPHENOXYPROPIONATES, DERIVATIVES THEREOF AND RELATED COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1988-05-11 EP disclosed
US-4725683-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1988-02-16 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed