Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780966 | 1.00 | GAA (0.66) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL29249699 | 1.00 | GAA (0.66) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL9506278 | 0.90 | KMT2A (0.63) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL12667937 | 0.84 | GAA (0.59) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL28746514 | 0.84 | ALDH1A1 (0.64) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL31107960 | 0.83 | KMT2A (0.54) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL15291914 | 0.83 | KMT2A (0.54) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL10563315 | 0.82 | KMT2A (0.58) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL17070609 | 0.82 | GAA (0.67) | GAAALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL30336909 | 0.82 | KMT2A (0.61) | GAAALDH1A1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |