Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280240 | 0.87 | CACNA1C (0.48) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7437834 | 0.87 | GAA (0.46) | GAATSHRCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9506294 | 0.84 | GAA (0.33) | GAATSHRCACNA1FCACNA1DCACNA1S | |
| Hydrochloric Acid SCHEMBL7272589 | 0.79 | LMNA (0.37) | GAATSHRCACNA1CKDM4ELMNA | |
| SCHEMBL10786109 | 0.76 | TSHR (0.47) | GAATSHRCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7271327 | 0.75 | CACNA1C (0.60) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9691213 | 0.73 | TSHR (0.44) | GAATSHRCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7273003 | 0.72 | CACNA1C (0.46) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7273014 | 0.72 | CACNA1C (0.46) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7280639 | 0.71 | LMNA (0.54) | GAATSHRCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361382-B1 | ANTIEPILEPTIC PYRAZOLOPYRIDINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-16 | — | — | EP | claimed |