Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503789 | 0.91 | TRPV1 (0.49) | TDP1RXFP1MEN1KMT2AMAPT | |
| SCHEMBL9506643 | 0.86 | RXFP1 (0.49) | TDP1RXFP1MEN1KMT2AMAPT | |
| SCHEMBL9504693 | 0.84 | IL2 (0.52) | MEN1KMT2AMAPTHTTALDH1A1 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.83 | TDP1 (0.70) | TDP1RXFP1MEN1KMT2AMAPT | |
| SCHEMBL9505640 | 0.78 | TRPV1 (0.50) | RXFP1MEN1KMT2AMAPTHTT | |
| SCHEMBL8624438 | 0.77 | TDP1 (0.62) | TDP1RXFP1ALDH1A1SMN1; SMN2RORC | |
| SCHEMBL11254390 | 0.76 | TDP1 (0.51) | TDP1RXFP1MEN1KMT2AMAPT | |
| SCHEMBL11253045 | 0.76 | TDP1 (0.59) | TDP1RXFP1MEN1KMT2AMAPT | |
| Chlorbenzuron SCHEMBL5177776 | 0.76 | GCGR (0.68) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8622701 | 0.76 | TDP1 (0.55) | TDP1RXFP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318882-B1 | (THIO)BENZOYL UREAS, FUNCTIONAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND PESTICIDAL USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | claimed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | claimed |
| US-4966902-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |