Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 2/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503789 | 0.89 | TRPV1 (0.49) | IL2TLR8TLR7MEN1KMT2A | |
| SCHEMBL9504696 | 0.87 | MEN1 (0.49) | IL2TLR8TLR7MEN1KMT2A | |
| SCHEMBL9506687 | 0.84 | TDP1 (0.56) | MEN1KMT2ACNR1RAB9AMAPT | |
| SCHEMBL30499684 | 0.81 | MAPT (0.62) | TLR7MEN1KMT2ARAB9AMAPT | |
| SCHEMBL7607258 | 0.81 | MAPT (0.62) | TLR7MEN1KMT2ARAB9AMAPT | |
| Penfluron SCHEMBL117735 | 0.81 | EPHX2 (0.60) | IL2TLR7MEN1KMT2ARAB9A | |
| SCHEMBL9326300 | 0.79 | EPHX2 (0.57) | IL2TLR7MEN1KMT2ARAB9A | |
| Diflubenzuron SCHEMBL42416 | 0.78 | RAB9A (0.59) | MEN1KMT2ACNR1RAB9AMAPT | |
| Diflubenzuron SCHEMBL18837607 | 0.78 | RAB9A (0.59) | MEN1KMT2ACNR1RAB9AMAPT | |
| SCHEMBL9505640 | 0.77 | TRPV1 (0.50) | MEN1KMT2ARAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318882-B1 | (THIO)BENZOYL UREAS, FUNCTIONAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND PESTICIDAL USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | claimed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | claimed |
| US-4966902-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |