Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503899 | 0.76 | CES1 (0.35) | CES1ALDH1A1TYMSCYP3A4HSD17B10 | |
| SCHEMBL2892505 | 0.75 | CFTR (0.53) | S100A4CFTRGOPCLMNANPSR1 | |
| SCHEMBL29963323 | 0.75 | CFTR (0.53) | S100A4CFTRGOPCLMNANPSR1 | |
| SCHEMBL10710575 | 0.73 | MAPT (0.55) | AKR1A1AKR1B1S100A4PDK2CFTR | |
| SCHEMBL11823991 | 0.73 | PDK2 (0.44) | PPOXAKR1A1AKR1B1S100A4AVPR1A | |
| SCHEMBL3839131 | 0.72 | AVPR1A (0.50) | PPOXAKR1A1AKR1B1AVPR1ACYP11B1 | |
| SCHEMBL11837675 | 0.72 | PDK2 (0.39) | PPOXAKR1A1AKR1B1AVPR1APDK2 | |
| SCHEMBL5517802 | 0.70 | FTO (0.58) | AKR1A1AKR1B1CFTRGOPCLMNA | |
| SCHEMBL11011777 | 0.69 | CFTR (0.44) | AKR1A1AKR1B1S100A4PDK2CFTR | |
| SCHEMBL9506034 | 0.68 | NPSR1 (0.41) | AVPR1APDK2METAP1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |