Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | TYMS | P04818 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506034 | 0.71 | NPSR1 (0.41) | ALDH1A1CYP3A4HPGDHIF1AHSD17B10 | |
| SCHEMBL2892505 | 0.70 | CFTR (0.53) | TYMSALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29963323 | 0.70 | CFTR (0.53) | TYMSALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL1209316 | 0.68 | FTO (0.50) | AHRALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL9506749 | 0.67 | ALDH1A1 (0.63) | MAPK1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL5139378 | 0.67 | NSD2 (0.41) | CES1DHFRTYMSALDH1A1 | |
| SCHEMBL11299095 | 0.66 | TDP1 (0.72) | DHFRTYMSALDH1A1CYP3A4HPGD | |
| SCHEMBL8988060 | 0.64 | AHR (0.36) | MAPK1AHR | |
| SCHEMBL79833 | 0.64 | ALOX15 (0.48) | CES1MAPK1AHRTYMSALDH1A1 | |
| SCHEMBL9502953 | 0.64 | CES1 (0.39) | CES1DHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |