Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506859 | 0.82 | AGBL2 (0.41) | HSD17B10KDM4EGAAALDH1A1GLA | |
| SCHEMBL10485375 | 0.78 | TKT (0.33) | KDM4EALDH1A1TSHR | |
| SCHEMBL6263548 | 0.76 | NPSR1 (0.55) | NPSR1HSD17B10GPR17THRATHRB | |
| SCHEMBL14988768 | 0.74 | NPSR1 (0.57) | NPSR1GPR17THRATHRBKDM4E | |
| SCHEMBL10485433 | 0.74 | NOS3 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL7316886 | 0.72 | HSD17B10 (0.40) | NPSR1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL11472727 | 0.71 | NPSR1 (0.50) | NPSR1HSD17B10GPR17THRATHRB | |
| SCHEMBL1964714 | 0.71 | NPSR1 (0.53) | NPSR1HSD17B10GPR17THRATHRB | |
| SCHEMBL9164676 | 0.70 | KDM4E (0.31) | KDM4E | |
| SCHEMBL1856540 | 0.69 | NPSR1 (0.52) | NPSR1GPR17THRATHRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0297397-A2 | Preparation of diazo and azo compounds | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |