Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506877 | 1.00 | TNNC1 (0.42) | TNNC1ALOX5PDE5AABCG2CTNNB1 | |
| SCHEMBL9508296 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9506072 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9508944 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9506896 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9506969 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9508304 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9506886 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9506075 | 0.94 | TNNC1 (0.49) | TNNC1HPGD | |
| SCHEMBL9508951 | 0.94 | TNNC1 (0.49) | TNNC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |