Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029536 | 0.79 | TUBB4A (0.72) | ALDH1A1SMN1; SMN2MAPK1HTTTSHR | |
| SCHEMBL17014736 | 0.78 | CYP1A2 (0.74) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL21065118 | 0.78 | NR1H4 (0.60) | ALDH1A1RAB9ASMN1; SMN2HTTTSHR | |
| SCHEMBL31461058 | 0.78 | NPC1 (0.54) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL5327194 | 0.77 | NR1H4 (0.59) | ALDH1A1RAB9ASMN1; SMN2HTTTSHR | |
| Hydrochloric Acid SCHEMBL5327187 | 0.77 | NR1H4 (0.59) | ALDH1A1RAB9ASMN1; SMN2HTTTSHR | |
| SCHEMBL9508967 | 0.73 | POLB (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL23911673 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL12580552 | 0.73 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTTSHRHSD11B1 | |
| SCHEMBL24177376 | 0.73 | NPC1 (0.51) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325336-B1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| US-4929628-A | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) | 1990-05-29 | — | — | US | disclosed |
| EP-0325336-A1 | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-07-26 | — | — | EP | disclosed |
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |