⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL27712578 | 0.95 | — | — | |
| Benzene SCHEMBL28109029 | 0.87 | ALDH1A1 (0.40) | — | |
| 1,2-Dichloroethane SCHEMBL28978798 | 0.84 | — | — | |
| SCHEMBL9540531 | 0.82 | — | — | |
| SCHEMBL27986358 | 0.82 | CA5A (0.33) | — | |
| SCHEMBL254 | 0.82 | — | — | |
| SCHEMBL6681816 | 0.82 | — | — | |
| Ethyl Chloride SCHEMBL473306 | 0.80 | — | — | |
| Methylene Chloride SCHEMBL9185705 | 0.80 | — | — | |
| Methylene Chloride SCHEMBL18529805 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241669-B | Preparation method of fasudil hydrochloride | JILIN BROADWELL PHARMACEUTICAL CO LTD | 2013-07-31 | — | — | CN | claimed |
| CN-102241669-A | Preparation method of fasudil hydrochloride | JILIN BROADWELL PHARMACEUTICAL CO LTD | 2011-11-16 | — | — | CN | claimed |
| WO-2021109371-A1 | METHOD FOR PREPARING POLYETHER MODIFIED POLYORGANOSILOXANE | 江苏四新科技应用研究所股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| CN-104640856-B | Carbazole-containing sulfonamides as cryptochrome modulators | 复位治疗公司 | 2017-09-15 | — | — | CN | disclosed |
| CN-107021895-A | Antiseptic | 尔察祯有限公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-101765585-B | Antibacterial agent | 尔察祯有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-105283458-A | Preparation of tert-butyl 4- ((1R,2S,5R) -6- (benzyloxy) -7-oxo-1, 6-diazabicyclo [3.2.1] octane-2-carboxamido) piperidine-1-carboxylate | MERCK SHARP & DOHME | 2016-01-27 | — | — | CN | disclosed |
| CN-102827067-B | Beta-lactamase inhibitor | SCHERING CORPORATION (US) | 2015-09-23 | — | — | CN | disclosed |
| CN-101918407-B | Beta-lactamase inhibitors | MERCK SHARP & DOHME | 2014-02-26 | — | — | CN | disclosed |
| CN-102241669-B | Preparation method of fasudil hydrochloride | JILIN BROADWELL PHARMACEUTICAL CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-103145695-A | Novel process for preparing fasudil hydrochloride | WISDOM PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-100551944-C | Polymer solid electrolyte | NIPPON SODA CO (JP) | 2009-10-21 | — | — | CN | disclosed |
| CN-101357986-A | Polyethylene glycol functional derivative and preparation method thereof | KANGDA MEDICAL SCIENCE AND TEC (HK) | 2009-02-04 | — | — | CN | disclosed |
| CN-1668662-A | Solid polymer electrolyte | NIPPON SODA CO (JP) | 2005-09-14 | — | — | CN | disclosed |
| CN-1083831-C | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1295064-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1209119-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 1999-02-24 | — | — | CN | disclosed |
| CN-1190395-A | Substituted (sulfonic, sulfinic, sulfonamido or sulfonamido) N- [ aminoiminomethyl) phenylalkyl ] -azaheterocyclic amide compounds | RHONE POULENC RORER PHARMA (US) | 1998-08-12 | — | — | CN | disclosed |
| EP-0548347-A1 | PHOTOGRAPHIC ELEMENTS CONTAINING 2-EQUIVALENT PYRAZOLONE COUPLERS AND PROCESS FOR THEIR USE | EASTMAN KODAK COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| CN-86108740-A | Process for preparing herbicidal sulfonamides | — | 1988-06-08 | — | — | CN | disclosed |