Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503948 | 0.83 | ALOX5 (0.53) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL9504272 | 0.79 | ALOX5AP (0.60) | ALOX5ALOX5AP | |
| SCHEMBL9590136 | 0.78 | ALOX5 (0.57) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7607544 | 0.78 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL9585158 | 0.78 | ALOX5 (0.57) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7608634 | 0.77 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL10682657 | 0.77 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7608640 | 0.74 | CYP1A2 (0.55) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| 2-(Phenoxymethyl)Benzothiazole SCHEMBL2245843 | 0.74 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7541426 | 0.74 | ALOX5 (0.74) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| US-5208344-A | Benzothiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-05-04 | — | — | US | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |
| US-5208344-A | Benzothiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |