Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335358 | 0.89 | GPBAR1 (0.60) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL9584531 | 0.87 | ALOX5 (0.61) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7593162 | 0.84 | GPBAR1 (0.67) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7599091 | 0.83 | GPBAR1 (0.65) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7599114 | 0.83 | GPBAR1 (0.65) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL9507002 | 0.81 | ALOX5AP (0.56) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7801672 | 0.80 | GPBAR1 (0.85) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7592902 | 0.80 | GPBAR1 (0.64) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL7595892 | 0.80 | GPBAR1 (0.64) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL8651397 | 0.80 | CYSLTR1 (0.63) | ALOX5APCYSLTR1GPBAR1CYSLTR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| US-5208344-A | Benzothiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |