Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10606286 | 0.91 | APLNR (0.38) | APLNRGRM2GRM3CYP2C19LMNA | |
| Bicarbonate SCHEMBL4003894 | 0.91 | APLNR (0.38) | APLNRGRM2GRM3CYP2C19LMNA | |
| SCHEMBL6714807 | 0.91 | GAA (0.38) | APLNRGRM2GRM3GAATHRB | |
| Cyclopentane SCHEMBL10864965 | 0.86 | APLNR (0.35) | APLNRCYP2C19LMNATSHRCYP2C9 | |
| SCHEMBL9485514 | 0.83 | APLNR (0.33) | APLNRGRM2GRM3CYP2C19GAA | |
| SCHEMBL18534475 | 0.80 | — | — | |
| SCHEMBL111139 | 0.80 | — | — | |
| SCHEMBL13783354 | 0.80 | — | — | |
| SCHEMBL1744322 | 0.80 | APLNR (0.35) | APLNRGRM2GRM3CYP2C19 | |
| Formic Acid SCHEMBL27756908 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398059-B1 | CYCLOPROPANOYLAMINOACID AMIDE DERIVATIVES | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0398059-A1 | Cyclopropanoylaminoacid amide derivatives | BAYER AG (DE) | 1990-11-22 | — | — | EP | disclosed |
| EP-0195201-B1 | PROCESS FOR THE PREPARATION OF N-ACYL-2,3-DEHYDRO CARBOXYLIC ESTERS | Degussa Aktiengesellschaft (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0257448-A2 | Optically active cyclopropanecarboxamides | NIHON BAYER AGROCHEM K.K. (JP) | 1988-03-02 | — | — | EP | disclosed |
| EP-0195201-A2 | Process for the preparation of N-acyl-2,3-dehydro carboxylic esters | Degussa Aktiengesellschaft (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0042107-B1 | DIHYDROPYRIDAZINONES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1985-04-03 | — | — | EP | disclosed |
| EP-0042107-A1 | Dihydropyridazinones, processes for their preparation and pharmaceutical compositions containing these compounds | BASF Aktiengesellschaft (DE) | 1981-12-23 | — | — | EP | disclosed |