Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9660887 | 0.88 | APLNR (0.38) | APLNRCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL9485514 | 0.86 | APLNR (0.33) | APLNRGRM2GRM3CYP2C19 | |
| Carbamic Acid SCHEMBL9658814 | 0.83 | ACHE (0.39) | APLNRGRM2GRM3CYP2C19 | |
| SCHEMBL9507172 | 0.80 | APLNR (0.36) | APLNRGRM2GRM3CYP2C19 | |
| SCHEMBL9652210 | 0.79 | — | — | |
| SCHEMBL16086835 | 0.78 | — | — | |
| SCHEMBL27735 | 0.78 | — | — | |
| SCHEMBL16086988 | 0.78 | — | — | |
| Bicarbonate SCHEMBL9484911 | 0.78 | APLNR (0.35) | APLNRCYP2C19 | |
| Ammonia Solution, Strong SCHEMBL8355302 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2385945-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | Bayer Pharma Aktiengesellschaft (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041896-B2 | Virtualization platform with dedicated cache access | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |
| EP-0461502-B1 | Azolyl propanol derivatives | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| EP-0461483-B1 | Method for the production of benzyl ketones | BAYER AG (DE) | 1995-11-02 | — | — | EP | disclosed |
| EP-0351647-B1 | 2,2-DIFLUOROCYCLOPROPYL DERIVATES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0461483-A2 | Method for the production of benzyl ketones | BAYER AG (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0461502-A2 | Azolyl propanol derivatives | BAYER AG (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0351647-A2 | 2,2-Difluorocyclopropyl derivates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0351646-A2 | Hydroxyalkinyl-azolyl derivatives | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |