Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823636 | 0.88 | PTGS2 (0.45) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL17243939 | 0.83 | PDE3B (0.40) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL11169920 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL8130587 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTPDE3B | |
| SCHEMBL10751045 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL24690678 | 0.79 | PDE3B (0.43) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL25329804 | 0.79 | FASN (0.42) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL23181611 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL16363013 | 0.78 | PTGS2 (0.39) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL16259365 | 0.78 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |