SCHEMBL9507251

SCHEMBL9507251

O=C/C(=C\c1cocn1)c1ccc(F)cc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.34
KMT2A Q03164 1/20 0.34
BCL2L1 Q07817 1/20 0.33
BAD Q92934 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LTA4H P09960 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
P4HTM Q9NXG6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507254 1.00 NQO2 (0.34) NQO2KMT2ABCL2L1BADCES2
SCHEMBL9507219 0.74 NQO2 (0.35) NQO2KMT2ABCL2L1BADCES2
SCHEMBL9509537 0.74 TDP1 (0.47) KMT2A
SCHEMBL9507222 0.74 NQO2 (0.35) NQO2KMT2ABCL2L1BADCES2
SCHEMBL9509534 0.74 TDP1 (0.47) KMT2A
SCHEMBL9508645 0.73 LTA4H (0.41) NQO2KMT2ABCL2L1BADCES2
SCHEMBL9508614 0.73 KDM4E (0.39) NQO2KMT2ALTA4H
SCHEMBL9508638 0.73 LTA4H (0.41) NQO2KMT2ABCL2L1BADCES2
SCHEMBL9508620 0.73 KDM4E (0.39) NQO2KMT2ALTA4H
SCHEMBL9507425 0.71 KMT2A (0.49) NQO2KMT2ACES2CES1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0298380-B1 PROCESS FOR THE PREPARATION OF ALPHA-BETA-SUBSTITUTED ACROLEINS BASF Aktiengesellschaft (DE) 1993-09-29 EP disclosed
US-4920232-A CHEMICAL INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 1990-04-24 US disclosed
EP-0298380-A2 Process for the preparation of alpha-beta-substituted acroleins BASF Aktiengesellschaft (DE) 1989-01-11 EP disclosed