Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509534 | 1.00 | TDP1 (0.47) | TDP1NFE2L2KMT2AMEN1RAB9A | |
| SCHEMBL9507234 | 0.84 | RAB9A (0.51) | TDP1NFE2L2KMT2AMEN1RAB9A | |
| SCHEMBL9507236 | 0.84 | RAB9A (0.51) | TDP1NFE2L2KMT2AMEN1RAB9A | |
| SCHEMBL9507425 | 0.82 | KMT2A (0.49) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9507418 | 0.82 | KMT2A (0.49) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9508638 | 0.80 | LTA4H (0.41) | KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL9508645 | 0.80 | LTA4H (0.41) | KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL9508614 | 0.80 | KDM4E (0.39) | NFE2L2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9510998 | 0.80 | KMT2A (0.37) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9510992 | 0.80 | KMT2A (0.37) | KMT2AMEN1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298380-B1 | PROCESS FOR THE PREPARATION OF ALPHA-BETA-SUBSTITUTED ACROLEINS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| US-4920232-A | CHEMICAL INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| EP-0298380-A2 | Process for the preparation of alpha-beta-substituted acroleins | BASF Aktiengesellschaft (DE) | 1989-01-11 | — | — | EP | disclosed |