Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113998 | 0.88 | KDM4E (0.41) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL9772660 | 0.78 | KDM4E (0.41) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL7116438 | 0.75 | KDM4E (0.50) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8444568 | 0.74 | KDM4E (0.42) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL11665260 | 0.74 | KDM4E (0.39) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL10876453 | 0.72 | GRIN2D (0.42) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL5760512 | 0.71 | KDM4E (0.43) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL19610489 | 0.71 | KDM4E (0.58) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL10378711 | 0.70 | SMN1; SMN2 (0.39) | KDM4EKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL11098597 | 0.70 | KDM4E (0.36) | KDM4EKMT2AMEN1SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031794-B1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDACAO OSWALDO CRUZ (BR) | 2019-01-02 | — | — | EP | claimed |
| US-20160214926-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDACAO OSWALDO CRUZ (BR) | 2016-07-28 | — | — | US | claimed |
| EP-3031794-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | Fundação Oswaldo Cruz (BR) | 2016-06-15 | — | — | EP | claimed |
| EP-0412391-B1 | CYCLOPROPANE THIOCARBOXYLIC ACID AMIDES | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | claimed |
| JP-2072146-A | — | — | None | — | — | JP | disclosed |
| JP-2221245-A | — | — | None | — | — | JP | disclosed |
| CN-108912005-B | Diphenyloxyalkylamine derivatives and pharmaceutical compositions containing the same | 奥斯瓦道·克鲁兹基金会 | 2022-01-14 | — | — | CN | disclosed |
| CN-108912005-B | Diphenyloxyalkylamine derivatives and pharmaceutical compositions containing the same | 奥斯瓦道·克鲁兹基金会 | 2022-01-14 | — | — | CN | disclosed |
| EP-3031794-B1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDACAO OSWALDO CRUZ (BR) | 2019-01-02 | — | — | EP | disclosed |
| US-20160214926-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDACAO OSWALDO CRUZ (BR) | 2016-07-28 | — | — | US | disclosed |
| US-20160214926-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDACAO OSWALDO CRUZ (BR) | 2016-07-28 | — | — | US | disclosed |
| EP-3031794-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | Fundação Oswaldo Cruz (BR) | 2016-06-15 | — | — | EP | disclosed |
| EP-3031794-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | Fundação Oswaldo Cruz (BR) | 2016-06-15 | — | — | EP | disclosed |
| CN-105517991-A | Diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives, pharmaceutical compositions, use of said pharmaceutical compositions for treating, preventing or inhibiting chronic pulmonary inflammatory diseases and methods for treating or preventing said diseases | FUNDACAO OSWALDO CRUZ | 2016-04-20 | — | — | CN | disclosed |
| CN-105517991-A | Diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives, pharmaceutical compositions, use of said pharmaceutical compositions for treating, preventing or inhibiting chronic pulmonary inflammatory diseases and methods for treating or preventing said diseases | FUNDACAO OSWALDO CRUZ | 2016-04-20 | — | — | CN | disclosed |
| WO-2015017906-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | FUNDAÇÃO OSWALDO CRUZ (BR) | 2015-02-12 | — | — | WO | disclosed |
| JP-H02221245-A | PHENOXYPHENOXYALKYLAMINE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE | NIPPON SODA CO LTD | 1990-09-04 | — | — | JP | disclosed |
| JP-H0272146-A | CYCLOPROPANECARBOXYAMIDE AND INSECTICIDE CONTAINING THE SAME AND KILLING OF INSECT | BASF AG | 1990-03-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214926-A1 | DIPHENYLOXYALKYLAMINE DERIVATIVES AND ARYLOXYALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, USE OF SAID PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING OR INHIBITING CHRONIC PULMONARY INFLAMMATORY DISEASES AND METHOD FOR TREATING OR PREVENTING SUCH DISEASES | CFTR, NAT1, AADAC | KDM4E 1427/4885KMT2A 1555/4885MEN1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.