Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252625 | 0.81 | KDM4E (0.47) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5820320 | 0.80 | OPRM1 (0.54) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7073431 | 0.74 | POLB (0.56) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6002603 | 0.72 | LTA4H (0.49) | KMT2AMEN1SMN1; SMN2BCHEL3MBTL1 | |
| SCHEMBL88417 | 0.72 | AOC3 (0.54) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16371575 | 0.72 | AOC3 (0.54) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9507354 | 0.71 | KDM4E (0.45) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11634296 | 0.71 | KDM4E (0.39) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9628720 | 0.71 | BCHE (0.42) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| Water SCHEMBL1169336 | 0.70 | AOC3 (0.52) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246001-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-03-29 | — | — | EP | disclosed |
| EP-4027964-A1 | DENTAL COMPOSITION | Dentsply Sirona Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-11000454-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-05-11 | — | — | US | disclosed |
| WO-2021048313-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20190117523-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017198840-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246001-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000454-B2 | Dental composition | PPIP5K2, INPP5D, DCPS | KDM4E 3446/4885KMT2A 3095/4885MEN1 4196/4885 |
| US-20190117523-A1 | DENTAL COMPOSITION | PPIP5K2, INPP5D, DCPS | KDM4E 3446/4885KMT2A 3095/4885MEN1 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.