Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098541 | 0.87 | ALDH1A1 (0.56) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3259595 | 0.86 | USP2 (0.60) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL15550746 | 0.83 | CYP4F2 (0.58) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2010417 | 0.82 | USP2 (0.67) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2871402 | 0.82 | PPARD (0.58) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7235182 | 0.82 | USP2 (0.56) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2556550 | 0.81 | L3MBTL1 (0.59) | ALDH1A1MAPTMAPK1NPSR1KDM4E | |
| SCHEMBL12159945 | 0.80 | USP2 (0.51) | USP2ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL637156 | 0.80 | KDM4E (0.56) | ALDH1A1SMN1; SMN2NPSR1KDM4EL3MBTL1 | |
| SCHEMBL11825493 | 0.79 | GLA (0.68) | USP2ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298380-B1 | PROCESS FOR THE PREPARATION OF ALPHA-BETA-SUBSTITUTED ACROLEINS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| US-4920232-A | CHEMICAL INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| EP-0298380-A2 | Process for the preparation of alpha-beta-substituted acroleins | BASF Aktiengesellschaft (DE) | 1989-01-11 | — | — | EP | disclosed |