Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509864 | 0.98 | NAAA (0.48) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL9511078 | 0.98 | NAAA (0.48) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL9508048 | 0.98 | NAAA (0.48) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL9509884 | 0.98 | NAAA (0.48) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL9507698 | 0.98 | NAAA (0.48) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL9507791 | 0.94 | ALDH1A1 (0.47) | NAAAMAPTTSHRACE2CA1 | |
| SCHEMBL7223259 | 0.86 | CA1 (0.55) | NAAAMAPTEPHX1TSHRACE2 | |
| SCHEMBL7224695 | 0.86 | NAAA (0.50) | NAAAEPHX1TSHRCA1ALDH1A1 | |
| SCHEMBL9507495 | 0.86 | HSD17B10 (0.40) | MAPTTSHRACE2CA1ALDH1A1 | |
| SCHEMBL7222715 | 0.86 | CA1 (0.50) | NAAAEPHX1TSHRCA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |