Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 7/20 | 0.38 |
| ▸ | METAP1 | P53582 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506691 | 1.00 | REN (0.45) | RENLMNAL3MBTL1TDP1METAP2 | |
| SCHEMBL9503799 | 1.00 | REN (0.45) | RENLMNAL3MBTL1TDP1METAP2 | |
| SCHEMBL8910518 | 0.94 | REN (0.49) | RENLMNAL3MBTL1TDP1METAP2 | |
| SCHEMBL7272557 | 0.94 | REN (0.49) | RENLMNAL3MBTL1TDP1METAP2 | |
| SCHEMBL5709598 | 0.86 | REN (0.44) | RENMETAP2METAP1 | |
| SCHEMBL5709564 | 0.86 | REN (0.44) | RENMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL9848324 | 0.86 | REN (0.47) | RENLMNAMETAP2METAP1 | |
| SCHEMBL8913327 | 0.84 | REN (0.50) | RENMETAP2METAP1 | |
| SCHEMBL8913322 | 0.84 | REN (0.50) | RENMETAP2METAP1 | |
| SCHEMBL8913320 | 0.84 | REN (0.50) | RENMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003472-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |