Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674649 | 0.88 | CRHBP (0.59) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL838254 | 0.86 | CRHBP (0.60) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL32679986 | 0.86 | HTT (0.55) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL11264333 | 0.85 | CRHBP (0.59) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL7379932 | 0.85 | ATM (0.75) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL9001693 | 0.84 | NPSR1 (0.61) | HTTALDH1A1ATMMEN1KMT2A | |
| SCHEMBL14875538 | 0.84 | ALDH1A1 (0.58) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL2112582 | 0.84 | ESR1 (0.54) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL1948739 | 0.84 | CES1 (0.66) | CRHBPCRHR2HTTCES1CES2 | |
| SCHEMBL21247872 | 0.84 | ALDH1A1 (0.67) | CRHBPCRHR2HTTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345551-B1 | EASILY FLOWABLE DELAYED CRYSTALLISING POLYARYLENE SULFIDE-MIXTURES | BAYER AG (DE) | 1993-09-08 | — | — | EP | claimed |