Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701035 | 0.70 | HCAR2 (0.44) | HCAR2ALDH1A1HAO1HCAR3RARB | |
| SCHEMBL14692540 | 0.69 | CYP2C19 (0.57) | KDM4EHCAR2ALDH1A1ATMHAO1 | |
| Hydrochloric Acid SCHEMBL8343134 | 0.67 | PDE4A (0.41) | XDHADORA2BADORA3ADORA2ACDK1 | |
| SCHEMBL15868907 | 0.66 | PARP1 (0.36) | KDM4EXDHLMNA | |
| SCHEMBL8525156 | 0.66 | PDE4A (0.43) | XDHADORA2BADORA3ADORA2ACDK1 | |
| SCHEMBL27640070 | 0.66 | GABRP (0.44) | KDM4EHCAR2GCGRALDH1A1HAO1 | |
| SCHEMBL9443825 | 0.65 | HRH3 (0.33) | XDHPAK1CDK1CCNB1 | |
| SCHEMBL3604705 | 0.65 | RARB (0.43) | KDM4EHCAR2ALDH1A1HCAR3RARB | |
| SCHEMBL3916646 | 0.65 | RARB (0.43) | KDM4EHCAR2ALDH1A1HCAR3RARB | |
| SCHEMBL8624574 | 0.65 | RARB (0.43) | KDM4EHCAR2ALDH1A1HCAR3RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551432-A1 | 4,5,6,7-TETRAHYDRO-1H-IMIDAZO 4,5-C]PYRIDINE DERIVATIVES AND ANALOGUES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-07-21 | — | — | EP | disclosed |