Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624574 | 1.00 | RARB (0.43) | RARBHCAR2MEN1ALDH1A1RARA | |
| SCHEMBL3916646 | 1.00 | RARB (0.43) | RARBHCAR2MEN1ALDH1A1RARA | |
| SCHEMBL1082565 | 0.98 | HCAR2 (0.41) | RARBHCAR2MEN1ALDH1A1RARA | |
| SCHEMBL23340379 | 0.93 | GABRP (0.45) | RARBHCAR2MEN1ALDH1A1MAPT | |
| SCHEMBL3924183 | 0.86 | KDM4E (0.41) | RARBHCAR2MEN1MAPTKMT2A | |
| SCHEMBL3614621 | 0.86 | KDM4E (0.41) | RARBHCAR2MEN1MAPTKMT2A | |
| SCHEMBL9691428 | 0.85 | KDM4E (0.38) | HCAR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9755023 | 0.84 | KDM4E (0.39) | HCAR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22202360 | 0.84 | KDM4E (0.39) | RARBHCAR2ALDH1A1KDM4EHCAR3 | |
| SCHEMBL27818098 | 0.79 | TDP1 (0.45) | MEN1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221315-A1 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2010-09-02 | — | — | US | disclosed |
| US-20100120864-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | GALLEY GUIDO | 2010-05-13 | — | — | US | disclosed |
| EP-2034962-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS AND PROCESS FOR THEIR PREPARATION. | Universidade de Lisboa (PT) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007142548-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120864-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | TAAR1, TAAR5, NPY2R | RARB 1390/4885HCAR2 109/4885MEN1 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.