SCHEMBL9507542

SCHEMBL9507542

CCCCc1nc2ccc(NC(=O)CCC)cc2n1Cc1cccc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.52
AGTR2 P50052 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507534 0.86 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL9510137 0.85 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL7053372 0.83 AGTR1 (0.73) AGTR1AGTR2
SCHEMBL9509656 0.81 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL8396565 0.80 AGTR1 (0.73) AGTR1AGTR2
SCHEMBL9040220 0.80 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL8391407 0.79 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL9509565 0.79 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL8396711 0.78 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL8393932 0.77 AGTR1 (0.74) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561939-A1 USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF DIABETIC NEPHROPATHY SMITHKLINE BEECHAM PLC (GB) 1993-09-29 EP disclosed
EP-0561896-A1 USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION SMITHKLINE BEECHAM PLC (GB) 1993-09-29 EP disclosed