Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510137 | 0.93 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL9509565 | 0.92 | AGTR1 (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL7053372 | 0.86 | AGTR1 (0.73) | AGTR1AGTR2PPARG | |
| SCHEMBL8396565 | 0.83 | AGTR1 (0.73) | AGTR1AGTR2PPARG | |
| SCHEMBL9507542 | 0.81 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8393932 | 0.80 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL8393762 | 0.79 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL9507534 | 0.79 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL8396711 | 0.78 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8396463 | 0.78 | AGTR2 (0.67) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561905-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF MACULAR DEGENERATION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |