SCHEMBL9507594

SCHEMBL9507594

CCCC(=O)N[C@@H](Cc1cnc(CCC)n1CCc1ccccc1Cl)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056871 0.92 PTGES (0.44)
SCHEMBL8957164 0.90 TP53 (0.40) MAPT
SCHEMBL7049832 0.86
SCHEMBL9507591 0.86 FNTA (0.39) MAPT
SCHEMBL8971306 0.85
SCHEMBL8957087 0.82
SCHEMBL7056939 0.82 PTGES (0.41)
SCHEMBL8971489 0.80
SCHEMBL8957101 0.80 TP53 (0.45)
SCHEMBL8957070 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561977-A1 USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE SMITHKLINE BEECHAM PLC (GB) 1993-09-29 EP disclosed
EP-0561896-A1 USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION SMITHKLINE BEECHAM PLC (GB) 1993-09-29 EP disclosed