SCHEMBL9507594

SCHEMBL9507594

CCCC(=O)N[C@@H](Cc1cnc(CCC)n1CCc1ccccc1Cl)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056871 0.92 PTGES (0.44) —
SCHEMBL8957164 0.90 TP53 (0.40) MAPT
SCHEMBL7049832 0.86 — —
SCHEMBL9507591 0.86 FNTA (0.39) MAPT
SCHEMBL8971306 0.85 — —
SCHEMBL8957087 0.82 — —
SCHEMBL7056939 0.82 PTGES (0.41) —
SCHEMBL8971489 0.80 — —
SCHEMBL8957101 0.80 TP53 (0.45) —
SCHEMBL8957070 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561977-A1 USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE SMITHKLINE BEECHAM PLC (GB) 1993-09-29 — — EP disclosed
EP-0561896-A1 USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION SMITHKLINE BEECHAM PLC (GB) 1993-09-29 — — EP disclosed
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