Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957161 | 0.92 | TP53 (0.40) | TP53MAPTADORA3ADORA2AADORA1 | |
| SCHEMBL7056869 | 0.91 | TP53 (0.45) | TP53MAPT | |
| SCHEMBL9507594 | 0.86 | MAPT (0.39) | MAPT | |
| SCHEMBL8971301 | 0.85 | TP53 (0.44) | TP53 | |
| SCHEMBL8971303 | 0.85 | TP53 (0.44) | TP53 | |
| SCHEMBL8957190 | 0.84 | TP53 (0.38) | TP53ADORA3ADORA2AADORA1DRD2 | |
| SCHEMBL8957111 | 0.83 | TP53 (0.44) | TP53MAPTADORA3ADORA2AADORA1 | |
| SCHEMBL8957103 | 0.83 | TP53 (0.44) | TP53MAPTADORA3ADORA2AADORA1 | |
| SCHEMBL7056937 | 0.83 | TP53 (0.46) | TP53MAPTADORA3ADORA2AADORA1 | |
| SCHEMBL8957074 | 0.82 | TP53 (0.45) | TP53ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561896-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561977-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |