SCHEMBL9507640

SCHEMBL9507640

Clc1cc2c(cc1Br)Sc1cc(Cl)c(Br)cc1S2

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.44
CSNK2A1 P68400 1/20 0.35
CISD1 Q9NZ45 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508099 0.78 AHR (0.37) AHR
SCHEMBL9510026 0.78 AHR (0.39) AHR
SCHEMBL11282194 0.78 AHR (0.55) AHRCSNK2A1
SCHEMBL3850787 0.75 AHR (0.58) AHRCSNK2A1CISD1
SCHEMBL10872182 0.69 AHR (0.57) AHRCSNK2A1CISD1
SCHEMBL29600009 0.69 AHR (0.57) AHRCSNK2A1CISD1
SCHEMBL8673651 0.67 AHR (0.44) AHRCSNK2A1
SCHEMBL1144865 0.67 BCHE (0.40)
SCHEMBL21218760 0.67 AHR (0.44) AHRCSNK2A1
SCHEMBL11593262 0.67 BCHE (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed