Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162196 | 0.80 | SCN4A (0.47) | PLAUELANESCN4AGAAMAPT | |
| SCHEMBL12126293 | 0.79 | NOS1 (0.46) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL348418 | 0.79 | NOS1 (0.46) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL29356511 | 0.78 | ALOX15 (0.44) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL3008191 | 0.77 | — | — | |
| SCHEMBL30171330 | 0.77 | ASAH1 (0.44) | NOS1PLAUELANEL3MBTL1 | |
| SCHEMBL12128384 | 0.76 | PLAU (0.51) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL19687206 | 0.76 | NOS1 (0.60) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL9503800 | 0.76 | NOS1 (0.50) | NOS1PLAUELANEF2KLKB1 | |
| SCHEMBL23583965 | 0.76 | SCN4A (0.43) | PLAUELANESCN4AF2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547055-A1 | AGENTS FOR INCREASING BIOMASS PRODUCTION | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 1993-06-23 | — | — | EP | claimed |
| WO-1991018509-A1 | AGENTS FOR INCREASING BIOMASS PRODUCTION | STICKSTOFFWERKE AG WITTENBERG-PIESTERITZ (DE) | 1991-12-12 | — | — | WO | claimed |
| EP-3541805-B1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018097945-A1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |
| CN-104628468-A | Synergist for composite/compound fertilizer, as well as preparation method and using method thereof | ZHANG BIN | 2015-05-20 | — | — | CN | disclosed |
| WO-2007045758-A1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-04-26 | — | — | WO | disclosed |
| EP-0547055-A1 | AGENTS FOR INCREASING BIOMASS PRODUCTION | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 1993-06-23 | — | — | EP | disclosed |
| WO-1991018509-A1 | AGENTS FOR INCREASING BIOMASS PRODUCTION | STICKSTOFFWERKE AG WITTENBERG-PIESTERITZ (DE) | 1991-12-12 | — | — | WO | disclosed |