Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507868 | 0.78 | CES2 (0.52) | ALDH1A1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL13092377 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL30209768 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL8196836 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL6070552 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL6070548 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL3130853 | 0.74 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL13494354 | 0.74 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL9509026 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL1922201 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRCASP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348737-B1 | HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES | BAYER AG (DE) | 1993-08-04 | — | — | EP | claimed |