Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644419 | 0.75 | CYP2A6 (0.50) | TP53TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL643621 | 0.74 | CYP2A6 (0.48) | TP53TSHRCYP3A4TDP1CYP2A6 | |
| SCHEMBL1299258 | 0.74 | TP53 (0.37) | TP53TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL28957262 | 0.72 | POLB (0.40) | TP53TSHRCYP3A4CYP2A6LMNA | |
| SCHEMBL3922969 | 0.71 | — | — | |
| SCHEMBL1921786 | 0.71 | TP53 (0.30) | TP53 | |
| SCHEMBL4455873 | 0.71 | NR4A2 (0.43) | HSD17B10TDP1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL11030089 | 0.71 | TP53 (0.43) | TP53TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL6048390 | 0.70 | HSD17B10 (0.35) | TSHRCYP3A4HSD17B10TDP1LMNA | |
| SCHEMBL2250860 | 0.70 | CYP1A2 (0.39) | TP53CYP3A4HSD17B10TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241423-B1 | PROCESS FOR THE PRODUCTION OF POSITIVE IMAGES | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | disclosed |
| EP-0241423-A2 | Process for the production of positive images | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |