Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342732 | 1.00 | HIF1A (0.39) | HIF1AEPAS1ELANEMAPTEPHX2 | |
| SCHEMBL9769164 | 0.74 | MAPT (0.44) | ELANEMAPTPPARA | |
| SCHEMBL9769157 | 0.73 | MAPT (0.37) | ELANEMAPTPPARA | |
| SCHEMBL3923663 | 0.72 | MAPT (0.41) | ELANEMAPTPPARA | |
| SCHEMBL30982893 | 0.71 | TYR (0.64) | ELANE | |
| SCHEMBL19900674 | 0.71 | PTGS2 (0.52) | HIF1AEPAS1GPR84 | |
| SCHEMBL19900655 | 0.71 | PTGS2 (0.52) | HIF1AEPAS1GPR84 | |
| SCHEMBL26908600 | 0.71 | PTGS2 (0.52) | HIF1AEPAS1GPR84 | |
| SCHEMBL25961589 | 0.71 | PTGS2 (0.52) | HIF1AEPAS1GPR84 | |
| SCHEMBL12581712 | 0.71 | PTGS2 (0.52) | HIF1AEPAS1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365256-B1 | PROCESS FOR PREPARING 5-SUBSTITUTED-3-FURALDEHYDES | ALLERGAN, INC (US) | 1993-09-15 | — | — | EP | disclosed |
| US-4935530-A | Process for preparing 5-substituted-3-furaldehydes | ALLERGAN, INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0365256-A1 | Process for preparing 5-substituted-3-furaldehydes | ALLERGAN, INC (US) | 1990-04-25 | — | — | EP | disclosed |