Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923663 | 0.98 | MAPT (0.41) | MAPTSMN1; SMN2PTGS2PPARAELANE | |
| SCHEMBL25907674 | 0.92 | MAPT (0.38) | MAPTSMN1; SMN2 | |
| SCHEMBL9769157 | 0.78 | MAPT (0.37) | MAPTPTGS2PPARAELANECYP3A4 | |
| SCHEMBL9507890 | 0.74 | HIF1A (0.39) | MAPTPPARAELANE | |
| SCHEMBL22342732 | 0.74 | HIF1A (0.39) | MAPTPPARAELANE | |
| SCHEMBL13381376 | 0.73 | — | — | |
| SCHEMBL30982893 | 0.73 | TYR (0.64) | ELANE | |
| SCHEMBL11407867 | 0.73 | PPARA (0.41) | PTGS2PPARAELANECYP3A4 | |
| SCHEMBL11858889 | 0.72 | MAPT (0.86) | MAPTSMN1; SMN2ELANE | |
| SCHEMBL11859633 | 0.72 | MAPT (0.86) | MAPTSMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |