Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508005 | 0.87 | SMN1; SMN2 (0.54) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1663739 | 0.86 | MAPT (0.56) | GRIK1MAPTALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4014462 | 0.83 | ALDH1A1 (0.64) | MAPTALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL5156571 | 0.81 | SMN1; SMN2 (0.67) | GRIK1MAPTALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7861107 | 0.81 | CXCR1 (0.63) | MAPTTDP1SMN1; SMN2CXCR1CXCR2 | |
| SCHEMBL9507967 | 0.80 | MAPT (0.51) | GRIK1MAPTALDH1A1CYP3A4ALOX15 | |
| SCHEMBL21750971 | 0.80 | MAPK1 (0.62) | MAPTALDH1A1CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL10542066 | 0.79 | ALDH1A1 (0.55) | GRIK1MAPTALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7974577 | 0.79 | ALDH1A1 (0.55) | GRIK1MAPTALDH1A1CYP3A4ALOX15 | |
| SCHEMBL3694733 | 0.78 | MAPT (0.77) | GRIK1MAPTALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317645-B1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4980287-A | ANTIINFLAMMATORY AGENTS; INHIBITOR OF DEGENERATION AND DESTRUCTION OF TISSUES | TEIJIN LIMITED (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0317645-A1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1989-05-31 | — | — | EP | disclosed |