Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | RARA | P10276 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507976 | 0.92 | RARB (0.70) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL10490937 | 0.90 | RARB (0.72) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL5065174 | 0.84 | RARB (0.65) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL10774091 | 0.84 | RARB (0.65) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL9394701 | 0.84 | RARB (0.61) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL4330679 | 0.84 | RARB (1.00) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL27595236 | 0.84 | RARB (0.76) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL8526681 | 0.84 | RARB (0.61) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL8025722 | 0.84 | RARB (0.74) | RARBALDH1A1RARAMEN1MAPT | |
| Paraben SCHEMBL11510587 | 0.83 | RARB (0.78) | RARBALDH1A1RARAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |