Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733311 | 0.95 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL11730871 | 0.94 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL2442335 | 0.93 | CNR2 (0.48) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL11730330 | 0.90 | CNR2 (0.46) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL9510729 | 0.90 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL11729347 | 0.88 | ICMT (0.47) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL11725382 | 0.87 | ICMT (0.49) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL11729719 | 0.87 | ICMT (0.49) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL9514595 | 0.86 | NPC1 (0.68) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL141889 | 0.86 | NPC1 (0.68) | MEN1KMT2ANPC1RAB9ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446554-B1 | PREPARATION OF A N-SUBSTITUTED PHENYLENEDIAMINE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5068439-A | Chemical intermediates for dyes, drugs, agricultural products and as antoxidants or stabilizers for rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0446554-A1 | Preparation of a N-substituted phenylenediamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4968843-A | FROM 4-HYDROXYDIPHENYLAMINE; EXCELLENT YIELDS OF HIGH PURITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4051067-A | Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkyleneamines and arylenediamines | MONSANTO COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4016198-A | Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkylene-amines and arylenediamines | MONSANTO COMPANY (US) | 1977-04-05 | — | — | US | disclosed |