Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511293 | 1.00 | KMT2A (0.45) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL9511305 | 1.00 | KMT2A (0.45) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL13557184 | 0.78 | KMT2A (0.50) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL9203085 | 0.75 | HTT (0.51) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9203080 | 0.75 | HTT (0.51) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9203076 | 0.75 | HTT (0.51) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2733150 | 0.74 | TSHR (0.65) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL2733147 | 0.74 | TSHR (0.65) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL14159334 | 0.73 | ELANE (0.61) | KMT2AMEN1TSHRALDH1A1ATM | |
| SCHEMBL16104845 | 0.72 | ELANE (0.44) | KMT2AMEN1TSHRALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022829-C | Synthesis of beta-lactams with metal compounds | UNIV UTRECHT (NL) | 1993-11-24 | — | — | CN | disclosed |
| EP-0281177-B1 | A SYNTHESIS FOR BETA-LACTAMS WITH THE AID OF A METAL COMPOUND | RIJKSUNIVERSITEIT UTRECHT (NL) | 1993-09-01 | — | — | EP | disclosed |
| US-4898955-A | INTERMEDIATE FOR PREPARING TRANS-B-LACTAMS | GIST-BROCADES N.V. (NL) | 1990-02-06 | — | — | US | disclosed |
| EP-0281177-A1 | A synthesis for beta-lactams with the aid of a metal compound | RIJKSUNIVERSITEIT UTRECHT (NL) | 1988-09-07 | — | — | EP | disclosed |
| CN-88100703-A | Synthesis of beta-lactams with metal compounds | — | 1988-08-17 | — | — | CN | disclosed |