Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203085 | 1.00 | HTT (0.51) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL9203080 | 1.00 | HTT (0.51) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL7635143 | 0.75 | KDM4E (0.46) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL31272103 | 0.75 | KDM4E (0.46) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL9511293 | 0.75 | KMT2A (0.45) | LMNAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL9511305 | 0.75 | KMT2A (0.45) | LMNAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL9508090 | 0.75 | KMT2A (0.45) | LMNAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL13704044 | 0.70 | GPR3 (0.60) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL22792110 | 0.70 | GPR3 (0.60) | HTTFFAR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL13704120 | 0.70 | GPR3 (0.60) | HTTFFAR1LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550635-B1 | FUSED RING ANALOGS OF NITROGEN CONTAINING NONAROMATIC HETEROCYCLES | PFIZER (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1992006079-A1 | FUSED RING ANALOGS OF NITROGEN CONTAINING NONAROMATIC HETEROCYCLES | PFIZER INC. (US) | 1992-04-16 | — | — | WO | disclosed |