SCHEMBL9508147

SCHEMBL9508147

[CH]=C(C)c1ccc(O[Si](C)(C)C)cc1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
GSTP1 P09211 3/20 0.34
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508152 0.82 GSTP1 (0.39) HTTGSTP1
SCHEMBL3866565 0.79 HTT (0.44) HTT
SCHEMBL2581744 0.76 KDM4E (0.44) HTT
SCHEMBL11381637 0.74 HAO1 (0.43) HTT
SCHEMBL13318435 0.73 TP53 (0.46)
SCHEMBL8463554 0.71 MAPT (0.32)
SCHEMBL10392636 0.69 CYP3A4 (0.46) HTT
SCHEMBL6519326 0.67 CA12 (0.46) HTTGSTP1MAOB
SCHEMBL4763549 0.66 CA1 (0.39)
SCHEMBL9720423 0.66 ESR1 (0.32) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0391191-B1 (METH)ACRYLIC POLYMERS GRAFTED WITH POLYCARBONATE CHAINS, THEIR MANUFACTURE AND USE BAYER AG (DE) 1993-09-01 EP disclosed
EP-0292785-B1 VINYL COPOLYMERES CONTAINING GRAFTED POLYCARBONATE CHAINS, THEIR MANUFACTURE AND USE BAYER AG (DE) 1991-06-05 EP disclosed