Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRNG | P07510 | 3/20 | 0.32 |
| ▸ | CHRND | Q07001 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953873 | 0.82 | TSHR (0.33) | OPRM1OPRL1 | |
| SCHEMBL28201252 | 0.77 | SLC6A4 (0.39) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL27330211 | 0.72 | TSHR (0.37) | OPRM1OPRL1 | |
| SCHEMBL27880024 | 0.71 | CHRNA1 (0.33) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNB1 | |
| SCHEMBL6954693 | 0.71 | CHRM1 (0.33) | — | |
| SCHEMBL7117350 | 0.69 | CHRM1 (0.31) | — | |
| SCHEMBL21333901 | 0.69 | HSD11B1 (0.39) | HSD11B1SLC6A3SLC6A4SLC6A2CHRNA1 | |
| SCHEMBL7453568 | 0.68 | GAA (0.34) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL28399986 | 0.68 | SLC6A2 (0.33) | SLC6A4SLC6A2 | |
| SCHEMBL29181879 | 0.68 | SLC6A3 (0.35) | HSD11B1SLC6A3SLC6A4SLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553284-A1 | SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992006076-A1 | SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |