Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510540 | 0.82 | PPARD (0.44) | PPARDMAOB | |
| SCHEMBL8874204 | 0.82 | MAOB (0.53) | MAOB | |
| SCHEMBL9507048 | 0.78 | PPARA (0.60) | PPARAPPARDMAOB | |
| SCHEMBL8067312 | 0.78 | XDH (0.55) | PPARDMAOB | |
| SCHEMBL9304221 | 0.75 | PPARA (0.67) | PPARAPPARD | |
| SCHEMBL9558448 | 0.75 | PPARA (0.52) | PPARAPPARDMAOB | |
| SCHEMBL3160539 | 0.75 | PTPN11 (0.60) | PPARAPPARDMAOB | |
| SCHEMBL3657870 | 0.75 | PPARD (0.56) | PPARDMAOB | |
| SCHEMBL538636 | 0.74 | PPARD (0.58) | PPARAPPARDMAOB | |
| SCHEMBL8069493 | 0.74 | XDH (0.56) | PPARDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310126-B1 | DERIVATIVES OF PYROCATECHOL-CARBOXYLIC ACID, THEIR PREPARATION AND USE AS ACTIVE INGREDIENTS IN MEDICINES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-08-18 | — | — | EP | claimed |
| EP-0310126-A2 | Derivatives of pyrocatechol-carboxylic acid, their preparation and use as active ingredients in medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-05 | — | — | EP | claimed |
| US-5191108-A | Lipoxygenase inhibitors, antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5025036-A | Antiinflammatory agents, gastrointestinal, cardiovascular and skin disorders | HOFFMANN-LA ROCHE INC. (US) | 1991-06-18 | — | — | US | disclosed |