Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557961 | 0.99 | PPARA (0.54) | PPARACYSLTR1PPARDHCAR2MAOB | |
| SCHEMBL9507048 | 0.88 | PPARA (0.60) | PPARAPPARDMAOBKAT8 | |
| SCHEMBL9558622 | 0.86 | MAOB (0.49) | PPARACYSLTR1MAOBFFAR1 | |
| SCHEMBL9558671 | 0.84 | PLA2G4B (0.55) | CYSLTR1FFAR1 | |
| SCHEMBL9557988 | 0.83 | PLA2G4B (0.57) | CYSLTR1 | |
| SCHEMBL9558352 | 0.80 | PPARA (0.47) | PPARAPPARDMAOB | |
| SCHEMBL9304221 | 0.80 | PPARA (0.67) | PPARAPPARDKAT8 | |
| SCHEMBL9558420 | 0.79 | THRA (0.49) | PPARDMAOB | |
| SCHEMBL9507025 | 0.79 | LCK (0.61) | PPARAKAT8 | |
| SCHEMBL10449025 | 0.79 | APP (0.47) | CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384350-B1 | DIHYDROXY NAPHTHALENE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| US-4937371-A | INHIBITING LIPOXYGENASE | HOFFMANN-LA ROCHE INC. (US) | 1990-06-26 | — | — | US | disclosed |