Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053983 | 0.90 | TSHR (0.40) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL27674430 | 0.89 | THRB (0.35) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL11136673 | 0.88 | TSHR (0.35) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL32674600 | 0.88 | TSHR (0.35) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL29385502 | 0.86 | THRB (0.39) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL228775 | 0.86 | THRB (0.39) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL28110850 | 0.84 | TSHR (0.46) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL32674604 | 0.83 | MEN1 (0.35) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL9316726 | 0.83 | MEN1 (0.35) | THRBTHRATSHREGFRMEN1 | |
| SCHEMBL32674605 | 0.82 | EGFR (0.33) | THRBTHRATSHREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5005011-A | — | — | None | — | — | JP | disclosed |
| JP-H055011-A | CAST MOLDING RESIN FOR LENS OF EYEGLASS | NIPPON OIL & FATS CO LTD | 1993-01-14 | — | — | JP | disclosed |